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🔬Absorption

BioPerine

BioPerine is a patented black pepper extract that may improve the absorption of other supplements. It is added as a bioavailability enhancer.

Clinical dosage

0mgUnderdosedEffective doseHigh dose
Minimum effective
5mg
Optimal dose
10mg
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Origin

Natural

BioPerine is a patented extract of black pepper (Piper nigrum), standardized to 95% piperine. Piperine is the compound that gives black pepper its bite. It's extracted from the fruits of the pepper plant, originally from India.

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Safety

BioPerine (piperine) is safe at the standard dose of 5-10mg per day. It improves absorption of other supplements by 30-2,000% depending on the compound (Shoba et al., 1998). It's the same substance you consume daily through black pepper, but in concentrated form.

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For comparison

A teaspoon of black pepper contains about 20-30mg of piperine. BioPerine in pre-workouts (5mg) is comparable to a quarter teaspoon of pepper. The difference is that BioPerine is standardized to 95% piperine, while pepper only contains 5-9%.

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Dosage by weight and gender

The effective BioPerine dose is 5-10mg per day, regardless of body weight (Shoba et al., 1998). There are no gender-specific recommendations. It works as a bioavailability enhancer, not as an active ingredient itself. Take it together with supplements whose absorption you want to improve.

Frequently asked questions

What does BioPerine do?

BioPerine (piperine) may improve absorption of other supplements by inhibiting enzymes in your gut that break down compounds before absorption. The best-known example is curcumin, whose absorption increases by 2,000% with piperine (Shoba et al., 1998). In pre-workouts it enhances absorption of ingredients like vitamins and amino acids.

Is BioPerine dangerous?

No, BioPerine is derived from black pepper, one of the most used spices in the world. At the standard dose of 5-10mg there are no side effects. Be cautious if you use medications though, as piperine can also increase drug absorption.

How much BioPerine per day?

5-10mg per day is the standard dose in clinical studies. Most pre-workouts contain 5mg. Taking more doesn't provide extra benefits. Take it at the same time as your other supplements for the best absorption effect.

Scientific sources

The clinical dosages on this page are based on peer-reviewed research.

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Pre-workouts with BioPerine

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