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Stimulant

Dynamine

Dynamine (methylliberine) may help increase energy and focus without significantly raising heart rate. The evidence is still limited.

Clinical dosage

0mgUnderdosedEffective doseHigh dose
Minimum effective
100mg
Optimal dose
200mg
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Origin

Natural

Dynamine (methylliberine) naturally occurs in kuding tea and certain coffee berries. It's structurally related to caffeine and theacrine. In supplements usually extracted from tea leaves or synthetically produced.

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Safety

Dynamine is relatively new as a supplement with limited research available. Short-term studies (up to 12 weeks) at doses of 100-200mg show no serious side effects. Due to the lack of long-term data, caution is warranted.

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For comparison

Dynamine works faster than caffeine, peaks within 30 minutes, but lasts shorter (1-2 hours vs 4-6 hours). Think of it as an espresso shot compared to slowly sipping a filtered coffee.

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Dosage by weight and gender

The typical dynamine dose in pre-workouts is 100-200mg per session. Body weight doesn't play a major role in dosing. There are no gender-specific recommendations due to limited research. Dynamine may work better combined with caffeine and theacrine (Compound Solutions, 2018).

Frequently asked questions

What does dynamine do?

Dynamine may increase alertness and energy without significantly affecting heart rate. It blocks adenosine receptors, similar to caffeine, but with faster and shorter action. It's often combined with caffeine for a broader energy profile.

Is dynamine dangerous?

No serious side effects have been reported at normal doses (100-200mg). However, research on dynamine is limited and relatively new, so long-term effects aren't fully mapped. Stick to the recommended dose.

How much dynamine per day?

Most pre-workouts contain 100-200mg dynamine. Don't take more than 400mg per day. Since dynamine works briefly (1-2 hours), it's best taken right before training.

Scientific sources

The clinical dosages on this page are based on peer-reviewed research.

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Pre-workouts with Dynamine

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