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HealthThin evidence

Digestive enzymes

Products with lipase, protease or lactase that support digestion of fat, protein or milk sugar.

What the research shows

Mixed or small evidence. The effect is uncertain.

De la Iglesia-García (2017) saw clearly better fat absorption in chronic pancreatitis, with two authors who received fees from a maker of enzyme products. Ojetti (2010) saw fewer symptoms after tilactase in lactose intolerance. Levine (2015) saw less fullness after a high-fat meal in healthy people, measured with a questionnaire in a small study.

Who it makes sense for: People with a diagnosed deficiency such as pancreatic insufficiency or lactase deficiency.

How we weigh evidence

Clinical dosage

0mgLightly dosedEffective doseHigh dose
Minimum effective
100mg
Optimal dose
1g

Scientific sources

The clinical dosages on this page are based on peer-reviewed research.

This page contains affiliate links. Rankings are purely data-based.

We keep the dosages and values on this page as accurate as possible based on selected studies. New research may change these values. Nothing on this page is medical advice. If you have any doubts, always consult a doctor.

Digestive enzymes: does it work? | WheyWijzer